The latest evidence that is meant to explain the biology for aging signifies that there is a clock or a counter in the cell of each and every human being’s body.
This clock or counter is controlled by a small DNA piece called a telomere, which is located at the end of every chromosome in the cell nucleus.
Each and every time the cell divides, telomere tends to become smaller and shorter until the cell reaches a stage where it is not able to divide and eventually dies.
Now with another latest invention, researchers have found out an enzyme known as telomerase can actually turn the counter on or off.
This particular enzyme has got the power to extend the lives of body cells & keep it dividing.
But it is found that in most cases of the cells in a human body, telomerase enzyme is often switched off and therefore the cells remain mortal & eventually die.
But in some other areas in the body such as the Hemopoietic cells, telomerase enzymes are switched on and hence the progenitors of the blood cells remain immortal.
But, the bad news is that cancer cells remain immortal. If we go by the telomere theory, it has been proved that cancererous cells do not age mainly due to the fact that it produces telomerase continuously thereby keeping it healthy, alive, youthful & continuously dividing.
Studies and research are being conducted to develop a type of treatment which will completely block telomerase enzymes in cancer cells & prevent them from dividing while at the same time lengthen telomere enzymes in aging cells of a human body thereby keeping their skin youthful & immortal.
The Aging Cell
There are many other faces of the aging cell. For one, there is where proteins are gummed up in a process known as cross-linking.
During this process, sugar molecules become attached to proteins and DNA resulting to a condition known as accumulated glycosolation end products or AGE. This can cause cataract in the eyes, clog in the blood vessels, and jam in the filter o the kidneys.
There are also free radicals at work. The free radicals that are generated by the breakdown of oxygen in the body damage the cells. The DNA in this case becomes torn apart that no rate of repair can actually keep up with the rate of damage.
The Disease: Aging; The Cure: HGH
Aging has previously been looked at as a natural course of life. Recent studies suggest, however, that aging is more like a disease. That is probably one of the reasons one aging person is different from another. They may have different manifestations of age, depending on their varied lifestyle.
Looking at aging in this sense allows researchers to develop theories regarding medical intervention. Indeed, this provides some helpful light as to how people can live in ageless beauty and youthful vibrancy throughout their lifespan.
Growth hormone may actually stop aging on the most fundamental level of the body’s organization – the cell, according to Grace Wong, Ph.D., a scientist in the department of molecular oncology at Genentech, the original makers of recombinant growth hormone.
As per Dr. Wong, aging occurs because of the breaking down of proteins inside the cell and also from the RNA and DNA and which function by providing the blueprint that is required for the production of proteins.
Hair, muscle, skin and bones are all being made with the help of proteins. These proteins tend to deteriorate along with the things that are made from them. The hair falls off, the skin begins to wrinkle, muscles begin to shrink and the bones begin to lose there density.
When it comes to the brain, the situation is worse mainly due to the fact that the main brain cells known as the neurons will not be able to regenerate. Due to this, a human being’s mental power begins to decline when they reach their middle age.
Antioxidants, such as vitamin C and vitamin E, can tackle these oxygen free-radicals and render the proteases inactive.
But growth hormone can act directly on the proteases and it works by stimulating a cellular defense force known as protease inhibitors.
This means that even though oxygen free-radicals are still present in the cell, the protease inhibitors prevent them from doing their damaging function. Talk about bulletproofing cells from the process of aging!
Protease inhibitors, such as ritonavir and saquinavir, are now being used in the treatment of AIDS, and preliminary reports indicate that they bring the virus down to virtually undetectable levels in affected people.
In laboratory experiments, growth hormone was able to protect animals against the free-radical-killing influences of radiation and hyperoxia. In one experiment, the animals were given a mixture of 98 percent oxygen, which could have been quite damaging and toxic but hgh saved them.
Dr. Wong believes that the decline in growth hormone with age may be a major factor in the loss of proteins that occurs in later life.
“As you age,” she says, “you are releasing less growth hormone, your immune response is decreasing, and at the same time the amount of oxygen free radicals are increasing.”
Without growth hormone in the cell to produce a bulletproofing effect by inducing protease inhibitors, the proteases activated by the oxygen free-radicals can destroy the cell’s proteins without any blockage.