GHB (Gamma Hydroxybutyrate) is a a naturally occurring substance found in every cell of the human body as well as the brain. It is both a precursor and a breakdown product of GABA (gamma-aminobutyric acid), a neurotransmitter that is involved in the regulation of the anterior pituitary gland, which secretes growth hormone.
Effects on GH
GHB is one of the most potent stimulators of growth hormone from the pituitary that has been discovered. A Japanese study of GHB found that a dose of 2.5 grams given intravenously to six young healthy men increased the levels of growth hormone ninefold within thirty minutes and rose to sixteen times over the baseline within one hour!
The latest report shows that GHB simultaneously stimulates slow-wave sleep (the deepest slumber) and growth hormone secre-tion.
In short, a small dose of GHB will lend the user 1-4 hours of relaxation, disinhibition*, giddiness, sociability, and/or Big Fun. That figure is serious; GHB is a quick, clean trip which leaves the user surprisingly clear-headed and sober. You can schedule a 5:00 job interview and take a small dose of GHB in the morning without having to worry about snapping into reality to find yourself with your teeth embedded in someone’s desk, wearing his tie as a loincloth. There is absolutely no “hangover” effect, although people who take larger doses and fall asleep may not be too happy about being awakened.
In the last few years, GHB (gammahydroxybutyrate) has become popular on the rave scene, with users enjoying an alcohol-like high with potent positive sexual effects
GHB is a fairly low toxicity substance with medical and recreational uses. It affects the release of dopamine in the brain, causing effects ranging from relaxation to sleep at low doses.
How it works
GHB can double the concentrations of the neurotransmitter dopamine in the brain. The release of growth hormone is under dopaminergic control in the hypothalamus and drugs that induce dopamine in the brain, such as L-dopa and bromocriptine (see below), are potent stimulators of GH. Unlike those drugs that work in a straightforward manner, GHB appears to take a circuitous route by inhibiting the release of dopamine from the nerve endings. This has the effect of creating higher levels of dopamine within the brain cells where it is stored. Some scientists have speculated that even after GHB wears off, the excess dopamine can be released into the synapses between nerve cells, leading to greater dopamine activity the next day.
Anti-aging benefits
Although the evidence is anecdotal, GHB users testify to its potency as an aphrodisiac. It also induces an extremely deep sleep at higher doses, which, like its effects on the libido, could be related to growth hormone release.
Clinical usage
GHB can be used safely at low doses to stimulate growth hormone. Or, 500 to 750 milligrams of GHB can be added to the stack of amino acids, along with 1 to 3 milligrams of melatonin , both of which will aid in sleeping.
Dosage
500 milligrams to 1 gram at bedtime as directed by physician.
Side effects
At high doses, it can induce a state of sleep so deep that the person can not be easily aroused. It has also been abused by bodybuilders who have taken many spoonfuls of the compound, with side effects, such as muscle spasms and twitching, associated with overuse. This led to the FDA withdrawing it from the market in 1990, although it is now generally available in health food stores.
Cautions
Buy pharmaceutical grade version manufactured by a known laboratory.