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Report on Serovital HGH review (anti aging supplement) by Natalie Holland

Serovital – Is it the perfect hGH product? Why I changed my stance on Serovital?

Written by Natalie Holland

Hi, I am Natalie, a blogger and product reviewer at MedReviews. I’ve been doing research on HGH and anti-aging products for like 8 years now, I’ve reviewed most of them, especially the better known ones and I do know a thing or two about HGH and why it’s real for anti aging. YES. HGH is great for better and a younger skin and overall fitness.

This article is about why I changed my stance on Serovital and do not currently rank it as the best hgh product for anti aging. I’ve tried to present the facts in straightforward manner in layman’s style while not using too much industry terms.

Editor’s Note:-

Serovital-hGH is a very popular anti-aging hgh supplement meant to be taken by both men and women. HGH supplements for anti aging are getting increasingly popular, however like the majority of products out there, Serovital is also primarily a blend of amino acids.

Although amino acids have been clinically proven to enhance hgh production in the body, this enhancing effect is quite minimal and doesn’t last long, because of the body’s homeostasis system. That’s why HGH supplements that “prolong” the effect of amino acids by using anti-somatostatin blend of ingredients like Alpha GPC and phosphatidylcholine are better working for the purpose of increasing HGH. Unfortunately Serovital misses on these ingredients.

Serovital also doesn’t have GABA and Deer antler velvet, making it reasonably effective yet mediocre anti-aging HGH product.

Please also read – How to pick a good HGH product and 7 Must Have ingredients in an HGH supplement.

Criteria for product ranking

These are the criteria on which I have reviewed the products :-

  1. Ingredients (Quality, Quantity and Diversity)
  2. Stand alone Clinical study (done on product itself, not individual ingredients and herbs)
  3. Price
  4. Medical recommendations
  5. User reviews

 Article Start

Serovital is everywhere now a days! Even celebrities can’t stop taking about it.

Dr. Oz recently talked about San Medica’s HGH study. Ever since he mentioned this study, people around the world have been talking about SeroVital.

The product was designed to eliminate the need for expensive prescription injections and increase HGH levels by 692 percent. Despite the applauding reputation behind SeroVital, does it deserve all of the hype it is getting?

Does the product deserve all the fame? What ingredients are involved?

SeroVital has amino acids that were specifically chosen to increase HGH production and to stimulate the pituitary gland.

L-Lysine HCl: This ingredient is useful for boosting immunity and protein production. It’s often employed to enhance athletic performance as it enhances “growth hormone” naturally. Research revealed that when lysine is combined with arginine and taken orally, it stimulates, “insulin and pituitary somatotropin (HGH) release.” But people must know the research involved 1200 mg of both arginine and lysine. doesn’t mention concentrations of any specific ingredient, so it is not possible to tell whether it has this amount of L-Lysine or not. Supposing SeroVital is a lot like Growth Factor 9 (another HGH based performance booster that uses exactly same SeroVital formula and ingredients), then possibilities are that the formula contains 2.9 grams of ALL ingredients combined.

L-Arginine HCl: This amino acid is necessary for production of nitric oxide, a compound that increases blood circulation and relaxes the blood vessels. According to researchers, “resting hormone growth responses increase with oral L-arginine ingestion.” However, again Arginine ought to be taken in 1200 mg doses if combined with L-lysine. Some studies did not demonstrate a HGH release until the dosage was increased to 5-9 g of Arginine alone.This is double the amount that SeroVital contains.

Why do people need to take high oral doses of these amino acids to produce any anti aging effects? And if people need to, then why these anti-aging products like Serovital don’t contain that much amount of amino acids like L-lysine and L-arginine? Read on to find out!

Oxo-Proline: This ingredient right here comes from glutamic acids.

Studies conducted on animals have suggested that Oxo-Proline decreases the non-enzymatic antioxidant defenses in the brain and causes “reactive species production”.

Animal studies also propose oxo-proline “results in protein oxidation.”

In a nutshell, oxo-proline has some bad effects!

Oxo-proline may “draw out oxidative stress,” or cause a discrepancy among reactive oxygen and body’s capability to restore the damaged cells. It produces toxic effects through the production of free radical. Concisely, adding with this amino acid might damage every cell component including lipids, DNA and proteins.

It can even accelerate aging, it seems, as one of the theories of “why aging occurs” is based on the “free radical damage to cells”. Not good. Is it?

N-Acetyl L Cysteine: It functions as a powerful antioxidant. Initially, it attaches to and neutralizes the free radicals.

Afterwards, it promotes the mixture of glutathione (an endogenous antioxidant). This is a more stable Cysteine form, which can be turned into cysteine in the cell.

Whereas NAC might be helpful for counteracting oxidative effects of oxo-proline, there is not sufficient research to prove any impact on production of HGH.

However, N-Acetyl L Cysteine has some remarkable anti aging, anti oxidant and anti inflammatory benefits. Men using this supplement have also observed higher testosterone levels, more vigor and energy.

Thumbs up to Serovital for including N-Acetyl L Cysteine in their formula.

L-Glutamine: During exercise, this amino acid operates as a buffer, preventing catabolism and soreness of muscle. Research shows HGH conserves muscle-free glutamine stores, enhancing the ability of body to work longer and harder. This also is a very good ingredient in “serovital”.

Studies have indicated that this ingredient increases the body’s ability to work harder, for a longer period of time.

Interestingly L-glutamine is also used as a “stress buster” because of its excellent properties to handle the physical and mental stress. Athletes and Bodybuilders love this because of the endurance it provides and how it keeps “cortisol” (stress hormone) in check without side effects.

AND if you’ve been searching on “HGH benefits”, then you might know that HGH is excellent for “stress control” and “sound sleep”. May be preservation of “muscle-free glutamine stores” is one mechanism by which HGH is able to control and lower down stress and induce the feeling of “positive” thinking and well-being. HGH works via a lot of mechanisms, that’s for sure.

So, whether you buy “Serovital” or not, take this message home – DO TAKE L-glutamine.

It’s an excellent anti aging supplement. It is backed actively by medical community and used extensively in hormone regulation regimens.

Schizonepeta (Aerial Parts):   This is the scientific term given to Japanese Catnip. Many claim that this herb is good treatment for allergic reactions as it inhibits cytokine and histamine release.

However, as with the other ingredients, there have not been any clinical studies done to determine if Schizonepeta’s has any effects on HGH.

So, those are the ingredients of Serovital.

Do they make an overall excellent product that you should invest in ? Did Dr. OZ really recommend it?

The hype!

It goes without saying that Dr. Oz’s name has been used around this product. Why? They do it in order to “hype” the product and to lend it credibility.

However, you must realize that Dr. Oz has never endorsed this specific product.

Dr. Oz has stated “I am not and have never been a paid spokesperson for any particular brand, supplement or product, because so many merchants are using my name and image to sell their products, it’s hard for me to catch everything.

Many who are advertising SeroVital tend to mention Dr. Oz’s “Recharge Your Body in 5 Ways in 5 Days!” episode. For this reason, consumers should take note of his exact words:

“A recent study showed that patients given a special blend of amino acids saw their HGH levels spike more than 6 times the levels they had at the beginning of the study.”

Dr. Oz did not mention the product specifically in any show he has done.

Should you buy SeroVital?

Many users obviously love the results they have witnessed while taking SeroVital, but personally, I am not overwhelmed with the product and its claims.

When I look at the ingredients in ServoVital, I see just a little more than amino acids. Many of the ingredients listed lack clinical studies to confirm positive effects on HGH. The one study that people should read, because it shows some hope for the product, has not been published, so it is not available to the general public. On top of all of this, the concentrations of the proprietary blend have not been revealed.

In a nutshell, here are my issues with this product.

1). It’s solely an amino acid based product.

Amino acids require high doses to be effective in releasing hGH naturally, according to the studies. But, in high oral doses they also produce side effects like nausea. Some anti aging experts believe they should be given via injections as this would be more effective and produce less side effects even if given in higher doses.

While other experts believe they can be effective in small oral doses if they are taken with other compounds (that work in synergy and as catalysts). Studies and user reviews now document that even in “small doses”, they can sufficiently enhance Growth hormone levels if they are taken with other synergistic ingredients like GABA, GTF Chromium, Colostrum, Phosphatidyl Choline etc. Find out more about these 7 MUST have ingredients in an HGH supplement.

Unfortunately, Serovital uses amino acids in “small amounts” (compared to medical studies) and does not include all these other synergistic ingredients.

2). Even if it’s primarily an amino acid blend, it still misses out on some other important amino acids like L-Ornithine, L-Tyrosine, L-Valine.

L-Arginine, L-lysine are not the only beneficial amino acids although they are the primary ones that had undergone an hGH study. There are other amino acids good for anti aging. One of the reasons why paleo diet works well for anti aging is that it includes so many amino acids.

In my opinion, “Deer antler velvet” should be a part of any hGH product because it is a natural blend of several amino acids.

And hGH itself is a peptide containing 91 amino acids. “Deer antler velvet” is one of those rare “gems of nature”. In case you’re searching for a product containing “Deer antler velvet”, check out this article.

3). Does your body really receive all those ingredients?

A product that is supposed to be a world class in terms of results must use mechanisms to enhance and guarantee effective absorption of the ingredients.

Fact is, when you take any oral supplement, a good amount of its ingredients get destroyed by your stomach acid. So, a supplement should either include ingredients that can enhance the absorption of other ingredients or use technology like “entric-coating” so that a good volume of ingredients in the pills don’t get destroyed stomach acid. Unfortunately, serovital doesn’t do that.

4). There are better products out there at the same price.

What about the side effects?

Products like Serovital and most other HGH supplements are devoid of side effects.

In fact, one reason they don’t employ amino acids in huge quantities(like those doses associated with medical studies on amino acids regarding their benefits on HGH production) is because amino acids like L-Arginine, L-Lysine in huge doses may lead to nausea, upset stomach, etc.

But these side effects are not common especially if you are not mega-dosing the amino acids.

Other ingredients are also safe.

In search of a better HGH product!

I’ve been a long time anti-aging enthusiast who just keeps on looking for better products out there.

While there are a lot of HGH scams going around, every now and then some good products do appear.

In my opinion any HGH supplement that makes use of these 7 MUST have ingredients has the potential of being an excellent HGH and anti aging product (based on clinical trials and those who’ve taken it successfully).


1.Deer antler velvet.

What is deer antler velvet? Just as you may have already guessed, it is velvet from deer antler. The antler grows at a rapid speed and when the antler has finally reached the full size, the cartilage turns into bone. Each spring, the cycle of the antler stars over. During this time, the antlers are harvested and used for medicinal purposes.

So, a good hgh product not only will have all the required amino acids for HGH release like L-Lysine, L-Arginine etc. , just like Serovital.

It also must contain “Deer antler velvet” – an added advantage over other HGH based products.

“Deer antler velvet” should be a part of any hGH product because it is a natural blend of several amino acids. And hGH itself is a peptide containing 91 amino acids.

Researchers have examined the medical properties of deer antler velvet. In New Zealand, Invermay Research Center’s GM, Dr. Peter Fennessy, discovered that the extract of deer antler increased growth of cells and it produced anti-tumor and anti-viral benefits as well.

While studying the aspects that caused deer antlers to grow at a rapid pace, they measured “IGF-1,” also known as a natural hormone factor. During this research, they discovered that there was a high level of IGF-1 in the deer’s blood while the antler was growing. It is now confirmed that deer antler velvet contains IGF-1.

In fact, Growth hormone and insulin-like growth factor-1 (IGF-1) are hormones that have very complicated and some inexplicable roles in the aging process. The relationship between growth hormone and IGF-1 is this: IGF-1 released by the liver in response to growth hormone, secreted by the pituitary. So, HGH stimulates IGF-1 production.

Studies have shown that Exercise can induce growth hormone release and thus IGF-1. And both hormones promotes growth and repair of skeletal muscle.

At young age our body makes good HGH and IGF-1 levels. The formation of IGF-1 results in lesser body fat as well as lean mass of muscle – which is why lots of teens are slim.

As the human body ages, we do not produce as much IGF-1 and  HGH. This is when the signs of aging (wrinkles, belly fat, fatigue, a decrease in sexual desire and loss of lean muscle) start to appear.

Back in 1974, two Russian physicians discovered that Pantocrine (Russian deer antler velvet) can be used to help the average athlete. When using deer antler velvet, the workout ability increases. Today, this is why you find that many athletes turn to HGH in order to help their performance levels.

Of course, you do not have to be an athlete to get the benefits of a good HGH supplement – the average human can use it.

For the normal people, who only want to become healthier and fitter, you might be quite surprised with the anti-aging and fitness outcomes you can accomplish, by using deer antler velvet.

2. Colostrum

There are many benefits to consuming Colostrum. Benefits include accelerated healing, an increase in immunity, anti aging and an increase in lean muscle and bone mass.

IGF-1 is so closely linked to HGH that it is utilized to measure production levels of HGH and many scientists believe that IGF-1 is in fact accountable for HGH anti-aging effects.

Colostrum is produced by the mammary glands of mammals right before they give birth and a couple of days after giving birth.

A good HGH supplement on the market usually contains Bovine Colostrum, which is almost identical to human Colostrum. In fact, Bovine Colostrum contains more beneficial properties.

3. Phosphatidyl Choline

It is a lecithin extract which is purified and acts as an exceptional emulsifier, enhancing the absorption of the various other nutrients contained in a supplement.

Phosphatidyl Choline emulsifies and disintegrates fat deposits inside the body as well, making it useful in preventing gallstones, heart disease, atherosclerosis, liver problems, memory loss, neurological disorders and depression.

There are several anti aging benefits of Phosphatidylcholine, often touted as the new wonder drug. It is the most abundant phospholipid component in all cells and is notably significant in keeping the brain cells healthy, so much so, that it is often given to people with brain related problems – dementia, memory loss, cognitive impairment etc.

With aging, levels of Phosphatidyl Choline in brain cell membranes decline with age, perhaps contributing to memory loss and other problems. Several studies have been done with phosphatidylcholine to investigate its effects on brain health with successful outcomes.

And, where does HGH get produced in your body? You’re right! In the BRAIN!!!

So, it makes sense why an HGH supplement must contain “Phosphatidyl Choline”. Healthy brain cells mean better HGH production.

Interestingly, Phosphatidyl Choline also supports liver function and that’s where IGF-1 is made.

I started taking “Phosphatidyl Choline” as a stand-alone supplement long ago when I realized it supports both brain and liver. Kind of like verifying the old saying that your mind and guts are “connected”.

Read more on Phosphatidyl Choline.


Gamma aminobutyric acid (GABA) is a gamma neurotransmitter that plays a significant role in hypothalamic-pituitary function in the human brain.

Inside the hypothalamus GABA is present in high concentrations. It is your hypothalamus that signals your pituitary glands to produce hGH, the magical hormone that keeps you young.

The pituitary glands are the master endocrine glands affecting every hormonal function in the body that includes Hormone Growth as well.

The region of hypothalamus is the brain’s posterior section and is the center of regulation for visceral (intuitive) functions like body temperature, sleep cycles, and pituitary gland’s activity.

It’s the most important region in your body when it comes to “regulating your hormones” and as you well know, your hormones regulate your fitness and health and of course anti-aging.

So, it makes sense to keep this region in ultimate health and prime fitness, more so, as it is where the production of HGH in your body takes place, which all these anti aging products like Serovital are supposed to enhance.

In my opinion, the KILLER combination of Phosphatidyl Choline and GABA ensures the proper functioning of hypothalamic-pituitary region. You can’t go wrong with this.

Literally hundreds of medical researches have been carried out on GABA in enhancing the functioning of “hypothalamic-pituitary region” and several researches on GABA’s capability to raise levels of growth hormone.

In addition, GABA is an excellent “sleep enhancer” leading to a sound and healthy sleep and studies point out that a deep sleep is great for not only anti-aging as in overall but also in increased production of HGH which is at its peak during “deep sleep”.

Studies also show “depressed” people are unable to enjoy “deep sleep” and that they also have low growth hormone levels. Another link!

5. Alpha GPC

 Alpha GPC is one hGH enhancing compound which many bodybuilders, athletes and even people interested in enhancing brain function are interested in. Extremely useful for those suffering from Alzheimer’s disease (AD) or depression, this ingredient has some amazing benefits and free from side effects.

Oral administration of Alpha GPC also increases the release of the neurotransmitter dopamine in the brain which is associated with feelings of wellness, libido, and motivation in life.

If you’ve been reading this article carefully, you must be seeing a pattern. An over-emphasis on the role of the brain!

Your brain, has lots to perform when it comes to your health and fitness. Brain is the region where most crucial hormones of your body like HGH, dopamine, LH, FSH are produced. That is why, probably, you’d need Alpha GPC Oral Spray which enhances neurons functioning.

Even more interestingly, Alpha GPC has been proven in clinical trials to increase HGH Release By Up To 4,100% During Workouts! (Compared To A 2.6% Increase *Without* Alpha-GPC)

It has also been scientifically proven to enhance cognitive function and hGH, although there are no established mechanisms and scientists don’t exactly know how it works although it is known to work and devoid of side effects.

GH decline is also associated with age-related cognitive impairment. The cholinergic system is an important part of the mechanism that regulates GH release stimulated by GHRH. Here GHRH (growth hormone-releasing hormone) is the hypothalamic hormone that triggers secretion of GH from the pituitary. Alpha GPC improves the age-related decline in GH responsiveness to GHRH, a result which has important implications for cognitive enhancement as well as for muscle building. Of course, GH releasers aren’t just for old folks suffering from alzheimers-alpha GPC and probably also CDP-choline stimulate GH release in younger subjects as well.  Read more.

For more information on 7 ingredients, read this post.

Bottom Line

I’ve been doing research on HGH products for like 8 years now, I’ve reviewed most of them, especially the better known ones and I DO know a thing or two about HGH and why it’s real for anti aging. YES. HGH is great for better and a younger skin and overall fitness.

Bottom line is – Serovital is NOT endorsed by Dr. OZ and currently it’s NOT my recommendation for an HGH based anti-aging product.

Please also read – How to pick a good HGH product and 7 Must Have ingredients in an HGH supplement.


Natalie Holland.